WebJul 15, 2024 · Dysphagia-Optimized IMRT Shows Significance in Head and Neck Cancer. Christopher Nutting, MD, discusses the results of a randomized phase 3 trial … WebSep 9, 2024 · DARS (ISRCTN:25458988) tested if using DO-IMRT to reduce RT dose to the dysphagia/aspiration related structures (DARS) improved swallowing function compared to S-IMRT. Materials and Methods Patients with T1-4, N0-3, M0 OPC/HPC were randomised 1:1 to S-IMRT (65 Gray (Gy)/30 fractions (f) to primary & nodal tumour; 54 Gy/ 30f to …
Modified intensity modulated radiotherapy reduces dysphagia in …
WebThe results of the DARS study by Nutting et al. clarified the advantage of limiting the mean doses to key swallowing structures like the pharyngeal constrictors with a significant reduction in patient reported swallowing difficulties … WebThe initial results from the Dysphagia-Aspiration Related Structures (DARS) trial, funded by Cancer Research UK and the National Institute for Health Research, ... “The optimised IMRT treatment will be a game changer for treating head and neck patients in the future. The DARS trial has proved the new technique can spare the swallowing muscles ... oral-b precision clean replacement
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WebDec 1, 2004 · Purpose To identify the anatomic structures whose damage or malfunction cause late dysphagia and aspiration after intensive chemotherapy and radiotherapy (RT) for head-and-neck cancer, and to explore whether they can be spared by intensity-modulated RT (IMRT) without compromising target RT. WebJul 1, 2024 · Increasingly, there is a focus to establish dysphagia-optimised IMRT (Do-IMRT) strategies [18], which could translate into improved long-term symptom burden … WebJun 8, 2024 · DO-IMRT, which has been pioneered by researchers from The Royal Marsden Hospital and The Institute of Cancer Research, London, is optimised to reduce the risk of swallowing difficulties, known as dysphagia. It does this by reducing radiation to the pharyngeal muscles, which support swallowing. ip lighting ltd